Systematic review · 2026
Chronic Pain: What 14 PBM Trials Found
A 2026 systematic review of photobiomodulation (PBM) across 14 randomized trials found that most included studies reported pain reductions, but varied conditions, devices, parameters, and limited follow-up prevented broad treatment recommendations. This is category-level evidence, not proof for the rePretty Mat.
Protocol
What was reviewed or tested
PBM compared with sham, placebo, or conventional care across heterogeneous chronic-pain protocols.
Selected outcomes
What the record reports
- Most included trials reported pain reductions, but technical heterogeneity and limited follow-up prevented broad standardized recommendations.
Required reading
Limitations
- Conditions, technical parameters, and follow-up periods varied substantially.
- A systematic review of clinical protocols cannot diagnose a user or prove the rePretty Mat treats pain.
Original source
Citation
Photobiomodulation in Chronic Pain: A Systematic Review of Randomized Clinical Trials. 2026.
Practical next steps
Compare the device, timing, and routine separately.
The next guides cover how to compare home devices, choose a starting schedule, and use a mat as part of an everyday routine.